SoftCare Clinic

Calculators

Insulin Resistance Calculator (HOMA-IR)

"Insulin resistance is a condition in which the insulin your body produces becomes less effective at lowering blood glucose, and it is especially common in women with Polycystic Ovary Syndrome (PCOS). HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a widely used index calculated from your fasting blood glucose and fasting insulin values to assess insulin resistance."

Insulin Resistance Calculator (HOMA-IR)

Enter your fasting glucose and fasting insulin values to calculate.

Threshold values vary with age, body mass index, population, and the insulin assay method used; the literature uses different thresholds ranging from 2,0 to 3,8.

Important notice

This tool is for informational purposes only; it is not a medical diagnostic tool. Results never replace a doctor's advice or a definitive diagnosis. Laboratory reference ranges can vary by laboratory and method; always review your result together with your doctor and the reference range used by the laboratory that performed the test.

"How is HOMA-IR calculated?"

"HOMA-IR = (fasting glucose [mg/dl] × fasting insulin [µU/mL]) / 405. If you enter glucose in mmol/l, the divisor is 22,5."

"How do I get these values measured?"

"For this calculation you need fasting glucose and fasting insulin values measured from a blood sample taken after 8–12 hours of fasting. You can find these values on your laboratory result report."

Frequently Asked Questions

What does it mean if my HOMA-IR is high?

It indicates that insulin resistance may be associated with PCOS, an increased risk of type 2 diabetes, and metabolic syndrome. A doctor's assessment is required for a definitive diagnosis.

When should the HOMA-IR test be done?

A doctor may recommend this test for women with menstrual irregularities, suspected PCOS, unexplained weight gain, or a family history of diabetes.

What should I do if my result is high?

See your doctor for follow-up. Do not treat yourself or use medication on your own.

References

  1. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Matthews DR, et al. Diabetologia, 1985.

Medically reviewed by Op. Dr. Şükrü Sanus, Obstetrician & Gynecologist · Last medical review: